Liporase - Hyaluronidase - Filler Dissolver

Pack Size: 10 vials x 1,500 IU Hyaluronidase (lyophilized powder)
Manufactured By: Daehan New Pharm Co., Ltd.
Made In: South Korea
Product Type: Enzymatic filler dissolver
Purpose: Dissolves hyaluronic acid-based dermal fillers and enhances fat-dissolving injections
Product Name: Liporase Hyaluronidase

Liporase Hyaluronidase is an enzyme-based injectable solution used to break down and dissolve hyaluronic acid (HA) fillers. When a filler placement goes wrong, whether due to overfilling, uneven distribution, migration, or accidental vascular injection, Liporase provides a fast, reliable correction. Manufactured by Daehan New Pharm in South Korea and approved by the KFDA, it is a trusted option for aesthetic practitioners who need precise, effective reversal of HA-based treatments.

What sets Liporase apart is that it targets only synthetic hyaluronic acid. It breaks down injected filler without interfering with the body's own naturally occurring HA, making it a targeted and tissue-friendly intervention.

How It Works

Liporase works by releasing hyaluronidase, a naturally derived enzyme, which breaks the molecular bonds in hyaluronic acid chains. Once injected into or around the treated area, it begins dissolving the filler rapidly. In most cases, visible reduction begins within a few hours, with full results becoming clear within 24 to 48 hours. It can also be combined with fat-dissolving serums to enhance their effectiveness by improving tissue permeability.

Composition

• Hyaluronidase 1,500 IU (lyophilized powder)
• 10 vials per pack
• Requires saline for reconstitution before use (not included)

Benefits of Liporase Hyaluronidase

• Rapidly dissolves HA-based dermal fillers
• Corrects overfilling, filler migration, and poor placement
• Acts as an emergency tool in cases of accidental arterial injection
• Boosts the efficacy of lipolytic (fat-dissolving) injections
• Sourced from naturally occurring enzymes
• Approved by KFDA, which meets strict Korean regulatory standards
• Results visible within 24-48 hours in most cases
• Minimally invasive with a straightforward application process

How To Use

1. Reconstitute 1 vial with 3cc of sterile saline for HA filler dissolution (use 5cc for fat-dissolving applications).
2. Apply a topical anesthetic or local anesthetic to reduce any discomfort at the injection site.
3. Inject the solution directly into or around the area where the filler needs to be dissolved.
4. Gently massage the treated area for several minutes to encourage even distribution.
5. A follow-up assessment is recommended 2–3 weeks after the procedure to evaluate results and determine if a second session is needed.

Safety and Storage

• Store in a cool, dry place away from direct sunlight and heat.
• Do not freeze or shake the vials aggressively.
• Keep out of reach of children.
• For professional use only, to be administered by trained aesthetic practitioners.
• Saline for reconstitution is not included and must be sourced separately.

Who Should Avoid

• Individuals with a known allergy to hyaluronidase or hyaluronate.
• Those with active inflammation, infection, or open wounds at the treatment site.
• Pregnant or breastfeeding women should consult a medical professional before use.
• Patients on blood-thinning medications or with clotting disorders should seek medical advice first.

Frequently Asked Questions

How quickly does Liporase start working?

The enzyme begins acting upon injection. Most patients see a noticeable reduction within a few hours, and full results are typically visible within 24 to 48 hours. Denser or more cross-linked fillers may take slightly longer.

Will it affect my natural hyaluronic acid?

No. Liporase is selective; it breaks down injected synthetic HA only. It does not interfere with the hyaluronic acid naturally produced by your body.

Is the procedure painful?

Discomfort is generally minimal. A local anaesthetic is typically applied beforehand to keep the patient comfortable during the injection.

Can Liporase be combined with other treatments?

Yes. It is commonly used alongside fat-dissolving injections to improve their penetration and speed up results. Always follow your practitioner's guidance on combination protocols.

How many sessions are needed?

In many cases, a single session is enough. However, a follow-up 2 to 3 weeks later allows the practitioner to assess residual filler and decide if a second application is required.

Need to reverse a filler result? Order Liporase Hyaluronidase and have the most trusted filler dissolver on hand, fast-acting, KFDA-approved, and made in South Korea.