{"product_id":"nextoxin-100iu-botulinum-toxin-type-a","title":"Nextoxin 100IU – Botulinum Toxin Type A - Nexus Pharma","description":"\u003cdiv class=\"product-block product-block--header product-single__header small--hide\"\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003ePack Size: \u003c\/strong\u003e\u003cspan\u003e1 vial × 100 Units per box\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003cstrong\u003eManufactured By:\u003c\/strong\u003e \u003c\/span\u003e\u003cspan\u003eNexus Pharma.\u003cbr\u003e\u003c\/span\u003e\u003cstrong\u003eMade In: \u003c\/strong\u003e\u003cspan\u003eSouth Korea\u003cbr\u003e\u003c\/span\u003e\u003cstrong\u003eProduct Type: \u003c\/strong\u003e\u003cspan\u003eBotulinum Toxin Type A - Lyophilized Powder for Injection\u003cbr\u003e\u003c\/span\u003e\u003cstrong\u003ePurpose: \u003c\/strong\u003e\u003cspan\u003eRelaxes targeted facial muscles to soften dynamic wrinkles and lines\u003cbr\u003e\u003c\/span\u003e\u003cstrong\u003eProduct Name: \u003c\/strong\u003e\u003cspan\u003eNextoxin 100IU\u003cbr\u003e\u003c\/span\u003e\u003cstrong\u003eRegulatory Approval: \u003c\/strong\u003e\u003cspan\u003eMFDS Korea (Ministry of Food and Drug Safety) approved for export\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNextoxin 100IU is a pharmaceutical-grade Botulinum Toxin Type A formulation manufactured by Nexus Pharma in South Korea. It is produced as a lyophilized powder using advanced vacuum-drying technology, a method that differs from conventional freeze-drying and offers measurable advantages in terms of product stability and purity. The result is a vial with a consistent potency profile, fewer inactive proteins, and a reliably reconstituted solution that behaves predictably across injections.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWhere some botulinum toxin products degrade faster or show batch-to-batch inconsistency, Nextoxin is engineered to hold up. The vacuum-drying process retains the structural integrity of the active toxin complex, meaning practitioners get the same clinical response from the first vial and the twentieth. For clinics handling volume, that kind of consistency matters far more than it might seem.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNextoxin carries MFDS Korea export approval and is manufactured under strict pharmaceutical quality controls at the Nexus Pharma facility in Gyeonggi-do, South Korea. It is intended solely for use by trained medical professionals and is not a consumer product.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eActions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNextoxin works by blocking the release of acetylcholine at the neuromuscular junction. When injected into a targeted muscle, the toxin binds to presynaptic nerve terminals and prevents the chemical signal that would normally trigger muscle contraction from being sent. The result is a temporary, controlled relaxation of that specific muscle group, without affecting surrounding tissue or motor function in adjacent areas.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIn aesthetic applications, this translates into a visible softening of dynamic wrinkles, the lines that form through repeated facial movement such as frowning, squinting, or raising the eyebrows. Because Nextoxin's vacuum-dried formulation maintains a lower inactive protein load, the diffusion profile stays controlled, reducing the risk of spread to unintended muscle groups. Effects are not permanent; the nerve terminal gradually recovers over months, which is why maintenance treatments are required to sustain results.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eIngredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eClostridium Botulinum Toxin Type A, 100 Units per vial\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eHuman Serum Albumin, 0.5 mg per vial (stabiliser)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eSodium Chloride, 0.9 mg per vial (tonicity agent)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eSterile water for injection, used for reconstitution (not included; to be prepared by practitioner)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eBenefits of Nextoxin 100IU\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eProduced with vacuum-drying technology for superior stability compared to standard lyophilisation\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eMinimal inactive protein content — reduces the risk of antibody formation with repeated use\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eConsistent potency across vials, giving practitioners a reliable dosing reference\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eControlled diffusion profile allows precise targeting without spread to adjacent muscles\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eFast onset — clinical muscle relaxation typically visible within 3 to 7 days of injection\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eLong-lasting effect with results maintained for 3 to 6 months depending on the treatment area\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eMFDS Korea approved for export, confirming regulatory compliance and product authenticity\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eSuitable for both aesthetic and therapeutic muscle-related indications\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eTrusted by medical practitioners for its predictable, reproducible clinical outcomes\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eHow To Use\u003c\/span\u003e\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\u003cspan\u003eReconstitute the lyophilized powder with sterile preservative-free normal saline (0.9% NaCl). The volume used depends on the target area and the practitioner's preferred dilution.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDraw up the reconstituted solution into an appropriate syringe using an aseptic technique. Use immediately after reconstitution for best results.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIdentify injection sites based on the target muscle group. Mark the sites with a skin marker if preferred for precision.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eInject intramuscularly or intradermally as required for the indication, using a fine-gauge needle. Apply gentle pressure post-injection to reduce bruising.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAdvise the patient to stay upright for at least 4 hours after treatment and avoid rubbing or massaging the injected area for 24 hours.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSchedule follow-up at 2 weeks to assess muscle response and determine if a touch-up dose is needed. Document dosage used per site for future reference.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eScope of Treatment\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eGlabellar lines (frown lines between the eyebrows) primary approved indication\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eForehead horizontal lines\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eCrow's feet (lateral canthal lines)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eBunny lines (nasalis wrinkles on nose bridge)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eBrow lifting micro-dose technique\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eMentalis dimpling (chin puckering correction)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eMasseter reduction for jawline slimming\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003ePlatysmal bands on the neck (Nefertiti lift)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eHyperhidrosis (excessive sweating) axillary and palmar\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eTherapeutic use for muscle spasm or medical muscle-related conditions under clinical supervision\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eSafety and Storage\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eUnopened vials must be stored under refrigeration between 2°C and 8°C. Do not freeze.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eKeep away from direct light and do not expose to heat sources.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eShelf life: up to 36 months from manufacturing date when stored correctly.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eOnce reconstituted, use within 4 hours. Discard any unused portion; do not store reconstituted solution.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eSingle-use vial only. Do not pool vials or reuse needles.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eCold chain must be maintained throughout transport and storage to preserve potency.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eKeep out of reach of children and store in a secure clinical setting.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eWho Should Avoid\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003ePatients with known hypersensitivity to Botulinum Toxin Type A or any excipient in the formulation (human serum albumin, sodium chloride).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eIndividuals with a diagnosed neuromuscular transmission disorder such as myasthenia gravis, Lambert-Eaton syndrome, or ALS.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003ePatients with active infection, inflammation, or skin compromise at the proposed injection site.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eTreatment for pregnant or breastfeeding women should be deferred until after this period.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003ePatients on aminoglycosides or other drugs that interfere with neuromuscular transmission, unless under strict medical supervision.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\u003cspan\u003eAnyone under 18 years of age.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli dir=\"ltr\"\u003e\n\u003cspan\u003eNon-medical individuals\u003c\/span\u003e\u003cspan\u003e: Nextoxin must not be purchased or administered without proper clinical training and licensure.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003e5 FAQs\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eHow quickly does Nextoxin take effect after injection?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eInitial muscle relaxation typically becomes visible within 3 to 5 days of treatment. The full effect is usually apparent by day 10 to 14. The timeline can vary slightly depending on the dose administered, the individual's muscle mass in the treated area, and the practitioner's injection technique. A follow-up assessment at 2 weeks is standard practice to evaluate the outcome.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eWhat makes Nextoxin different from other Botulinum Toxin Type A products?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe key difference lies in the manufacturing process. Nextoxin uses vacuum-drying rather than standard lyophilisation. This method results in a formulation with better structural preservation of the toxin complex, fewer inactive proteins, and a more stable product with a longer shelf life. For the practitioner, this means more consistent dosing behaviour and a lower theoretical risk of neutralizing antibodies developing with repeated treatments.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eHow long do the results of Nextoxin last?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIn most patients, the aesthetic effect of Nextoxin lasts between 3 and 6 months. High-movement areas such as the forehead and crow's feet may metabolise the product faster than lower-activity zones. Masseter reduction and hyperhidrosis treatments can sometimes last longer. Maintenance sessions are typically scheduled every 3 to 4 months to sustain the result.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eCan Nextoxin be combined with dermal fillers or other aesthetic treatments?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eYes, Nextoxin is commonly used alongside hyaluronic acid dermal fillers as part of a full facial rejuvenation plan. Botulinum toxin handles dynamic muscle activity while fillers address volume loss and static lines. When combining treatments in a single session, practitioners typically inject botulinum toxin before filler to allow proper positioning assessment. Combining with laser treatments, peels, or other injectables should be managed carefully with appropriate timing between sessions.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eWhat should patients avoid after receiving Nextoxin treatment?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAfter treatment, patients should remain upright for at least 4 hours. They should avoid rubbing, massaging, or applying pressure to the injected areas for 24 hours. Strenuous exercise, saunas, and excessive heat exposure should be avoided for the remainder of the treatment day. Alcohol should be avoided for 24 hours as it can increase bruising. Normal activities can typically resume on the same day, though any planned facials or aesthetic procedures near the treated area should be postponed for at least 2 weeks.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003ePrecision muscle control starts with the right formulation.\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eOrder Nextoxin 100IU today and give your clinic the stability, purity, and performance that South Korean pharmaceutical standards deliver.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ApniCare.Pk","offers":[{"title":"Default Title","offer_id":53777312121142,"sku":null,"price":12950.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0860\/0145\/1318\/files\/Nextoxin_100IU_Botulinum_Toxin_Type_A.png?v=1773591949","url":"https:\/\/apnicare.pk\/products\/nextoxin-100iu-botulinum-toxin-type-a","provider":"ApniCare.Pk","version":"1.0","type":"link"}